Polar Bioactive Constituents from Aerial Parts of Thymus longicaulis

Thymus longicaulis C. Presl., belonging to the Lamiaceae family, is a small aromatic perennial herb typical of the Mediterranean vegetation. This species, known in traditional phytoteraphy of Italy, has been extensively investigated in terms of chemical analysis and biological activity of its essential oils. Nevertheless, few data are available in the literature, regarding the chemical characterization of polar components of T. longicaulis. In this study, the phytochemical investigation of methanol extract of T. longicaulis through different chromatographic techniques, led to the isolation of thirteen compounds. The structures of rosmarinic acid and two derivatives, as well as that of flavones, triterpenes and a lignan have been elucidated on the basis of extensive NMR spectroscopic analyses. The evaluation of DPPH radical scavenging activity of pure compounds has been performed. Corresponding authors: Brigida, D’Abrosca. Department of Environmental Biological and Pharmaceutical Sciences and Technologies, Second University of Naples, Via Vivaldi 43, Caserta, Italy; Tel: +39-0823-274564; E-mail: [email protected] Received Date: 22 February, 2016 Accepted Date: 29 February, 2016 Published Date: 3 March, 2016 Citation: D’Abrosca, B., et al. Polar Bioactive Constituents from Aerial Parts of Thymus Longicaulis C. Presl. (2016) Lett Health Biol Sci 1(1): 14. Lett Health Biol Sci | volume 1: issue 1 www.ommegaonline.com